Wednesday, January 8, 2025

Top 3 Best Vitamin C for Anxiety and Depression


Vitamin C is an essential nutrient with powerful antioxidant properties that play a significant role in supporting mental health. It reduces oxidative stress, promotes neurotransmitter function, and helps manage the physiological effects of anxiety and depression. Below are the top three vitamin C brands highly regarded for their effectiveness and quality.

1. Jamieson Chewable Vitamin C 500 mg


Jamieson Chewable Vitamin C 500 mg stands out as an excellent choice for supporting mental health, particularly for individuals managing anxiety and depression. Its high-quality formulation uses naturally sourced ingredients, ensuring better absorption and gentle digestion compared to many other brands. The chewable format makes it convenient and pleasant to take, encouraging consistency, which is essential for maintaining adequate vitamin C levels. Vitamin C plays a critical role in reducing oxidative stress, supporting adrenal health, and promoting the production of neurotransmitters like serotonin. Jamieson's reputation for rigorous quality testing and its absence of artificial sweeteners or additives give it an edge over competing brands in delivering a trusted, effective supplement for mental well-being.

2, Webber Naturals Vitamin C Timed Release 


Webber Naturals Vitamin C Timed Release is an excellent option for supporting anxiety and depression due to its gradual release formula, which ensures a steady supply of vitamin C throughout the day. This sustained delivery helps stabilize cortisol levels and reduces oxidative stress, both of which are critical in managing mental health. Unlike other brands, Webber Naturals prioritizes purity, using non-GMO ingredients without artificial colors, preservatives, or sweeteners. This timed-release formulation minimizes fluctuations in vitamin C levels, making it particularly beneficial for those with heightened sensitivity to stress or mood instability, setting it apart as a trusted choice for long-term mental wellness support.

3, Nature's Bounty Vitamin C Supplement with Rose Hips


Nature's Bounty Vitamin C Supplement with Rose Hips is a great choice for supporting anxiety and depression, combining potent antioxidant support with added benefits from rose hips, which enhance vitamin C absorption and provide additional phytonutrients. This formulation aids in reducing oxidative stress and supporting adrenal health, which are vital for managing anxiety and improving mood. Compared to other brands, Nature's Bounty stands out for its affordability and commitment to quality, being free from artificial colors, flavors, and GMOs. The inclusion of rose hips makes it particularly effective for individuals seeking a natural and synergistic approach to mental health support.





How Vitamin C Supports Anxiety and Depression

Vitamin C plays a crucial role in mental health by:

  • Reducing Oxidative Stress: As a powerful antioxidant, vitamin C neutralizes free radicals that contribute to inflammation and stress-related damage in the brain.

  • Supporting Neurotransmitter Production: It is essential for the synthesis of serotonin and norepinephrine, which regulate mood and stress responses.

  • Lowering Cortisol Levels: Vitamin C helps regulate the adrenal glands, reducing cortisol, the hormone associated with stress.

  • Enhancing Immune Function: A healthy immune system can mitigate the physical toll of chronic stress and depression.

Conclusion 

Choosing the right vitamin C supplement can significantly enhance your mental health regimen. Jamieson Chewable Vitamin C 500 mg, Webber Naturals Vitamin C Timed Release, and Nature's Bounty Vitamin C Supplement with Rose Hips are three top-tier options that offer high-quality formulations, effective delivery methods, and proven benefits for anxiety and depression. Incorporating these supplements into your daily routine can support a healthier mind and body, helping you better manage stress and improve your emotional well-being.

Top 3 Best Vitamin B Complex for Anxiety and Depression



Vitamin B complex supplements are essential for managing anxiety and depression, as they support brain health, regulate neurotransmitters, and help combat stress. Choosing the right B complex supplement is critical to ensure quality, bioavailability, and effectiveness. Below are the top three vitamin B complex brands highly regarded for their ability to support mental health.


1, Jamieson Complex Ultra Strength Timed Release


Jamieson Complex Ultra Strength Timed Release is a reliable and innovative choice for managing anxiety and depression. This supplement provides a high-potency blend of essential B vitamins, including methylcobalamin (B12), pyridoxine hydrochloride (B6), and folic acid, delivered in a timed-release format to ensure steady and prolonged absorption throughout the day. This feature helps maintain consistent energy levels, supports neurotransmitter function crucial for mood stabilization, and reduces the risk of spikes or deficiencies. Jamieson’s products undergo rigorous quality testing, are non-GMO, and free from artificial colors or flavors. Compared to others, its timed-release design and affordable pricing make it a practical choice for individuals seeking reliable and long-lasting mental health benefits.

2. Webber Naturals Vitamin B Complex, Timed Release 


Webber Naturals Vitamin B Complex, Timed Release, is a strong contender for supporting anxiety and depression. This supplement offers a balanced mix of B vitamins, including B1, B6, B12, and folic acid, formulated for timed release to ensure gradual absorption and sustained benefits throughout the day. Its unique blend supports the nervous system, energy production, and neurotransmitter balance, all crucial factors in mood regulation. Webber Naturals is recognized for its commitment to quality, using non-GMO ingredients and adhering to stringent testing standards. Compared to other brands, its combination of affordability, sustained-release technology, and dependable quality makes it a practical choice for individuals seeking consistent mental health support.


3.  Nature’s Bounty B Complex w/Folic Acid plus Vitamin C


Nature’s Bounty B Complex w/Folic Acid plus Vitamin C is a versatile and affordable option for managing anxiety and depression. This formula combines essential B vitamins like B12, B6, and folic acid with added vitamin C, which enhances antioxidant support and immune health. The blend supports energy production, neurotransmitter function, and overall nervous system health. Nature’s Bounty is known for its rigorous quality assurance processes and use of non-GMO ingredients, making it a trustworthy choice. Compared to others, its added vitamin C and budget-friendly pricing make it an excellent choice for those seeking comprehensive mental health support without compromising on quality.




How Vitamin B Complex Supports Anxiety and Depression

Vitamin B complex supplements are critical for mental health as they:

  • Boost Energy Production: B vitamins help convert food into energy, combating fatigue often associated with depression.

  • Support Neurotransmitter Function: B6, B12, and folate play a crucial role in the production of serotonin, dopamine, and GABA, which regulate mood and stress levels.

  • Reduce Homocysteine Levels: Elevated homocysteine levels are linked to depression, and B vitamins help lower these levels, improving brain function.

  • Combat Stress: B vitamins, particularly B5 and B6, help regulate the adrenal glands, reducing the physical and mental effects of stress.

Conclusion 

Choosing the right vitamin B complex supplement can make a significant difference in managing anxiety and depression. Pure Encapsulations B-Complex Plus, Garden of Life mykind Organics B-Complex, and Solgar B-Complex "100" are three of the best options available, offering high-quality, bioavailable formulations that effectively support mental health. Incorporating these supplements into your routine, alongside a healthy diet and lifestyle, can help you achieve a calmer mind and improved emotional balance.


Monday, January 6, 2025

Best Magnesium Supplements for Anxiety and Depression: A Comprehensive Guide

 


Magnesium is an essential mineral that plays a key role in many bodily functions. Many studies suggest that magnesium supplements can help manage symptoms of anxiety and depression. Choosing the right magnesium supplement can improve mood and reduce feelings of stress.

With various forms available, such as magnesium citrate and magnesium glycinate, it’s important to know which ones are most effective for mental health. Some supplements may offer better absorption and fewer side effects. Understanding the options can lead to better choices for those seeking relief from anxiety and depression.

This blog post will explore the best magnesium supplements for anxiety and depression. Readers will find helpful information to guide them in selecting the most suitable options for their needs.

Understanding Magnesium's Role in Anxiety and Depression

Magnesium plays a significant role in mental health, particularly in managing anxiety and depression. This section highlights the types of magnesium supplements available, how magnesium affects brain function, and the research supporting its benefits.

Types of Magnesium Supplements

There are several forms of magnesium supplements, each with unique properties. Common types include:

  • Magnesium Citrate: Easily absorbed and commonly used for anxiety relief.

  • Magnesium Glycinate: Known for promoting calmness and improving sleep quality.

  • Magnesium Oxide: Often used to relieve constipation, but has lower absorption.

  • Magnesium Malate: May help reduce fatigue and improve mood.

Choosing the right type can depend on personal needs and how the body reacts. Always check with a healthcare professional before starting any supplement.

How Magnesium Affects the Brain

Magnesium influences various neurotransmitters, which are chemicals that transmit signals in the brain. It helps regulate:

  • Serotonin: Often called the "feel-good" hormone, important for mood stabilization.

  • Cortisol: The stress hormone; magnesium can help control its levels.

Low magnesium levels may lead to increased anxiety and depressive symptoms. The mineral helps reduce excessive neural activity, promoting relaxation and better overall emotional balance.

Research and Evidence

Research shows a link between magnesium deficiency and mood disorders. Some important findings include:

  • Studies indicate that individuals with anxiety often have lower magnesium levels.

  • A review of clinical trials found that magnesium supplementation can improve symptoms of depression.

  • Animal studies show that magnesium can have anxiolytic (anxiety-reducing) effects.

While more research is needed, current evidence suggests that adequate magnesium intake may support mental health and help manage anxiety and depression.

Selecting the Right Magnesium Supplement

Choosing the right magnesium supplement is essential for those seeking relief from anxiety and depression. It involves understanding specific factors, preferred forms of magnesium, and safe dosage levels.

Factors to Consider

Several factors play a key role in selecting a magnesium supplement. First, consider the reason for taking magnesium. Different forms may offer varying benefits. Next, look at the product's bioavailability. This indicates how well the body can absorb the magnesium.

Check for additional ingredients, as some supplements include herbs or vitamins that may enhance effects.

Lastly, confirm if the product is free from allergens and fillers, especially if there are dietary restrictions. Conducting a bit of research ensures that the chosen supplement meets personal health needs.

Recommended Best Magnesium Supplements For Anxiety and Depression

There are numerous brands of magnesium available. Some of the best recommended Magnesium Supplements for anxiety and depression include:



1, NOW Foods, Magtein, Magnesium L-Threonate



NOW Foods Magtein, Magnesium L-Threonate, is an excellent supplement for anxiety and depression, uniquely designed to support brain health and cognitive function. Unlike other forms of magnesium, magnesium L-threonate is specifically formulated to cross the blood-brain barrier, making it highly effective for improving mood, reducing stress, and enhancing mental clarity. NOW Foods stands out with its commitment to quality, utilizing non-GMO ingredients and rigorous third-party testing to ensure potency and purity. Compared to other magnesium supplements, Magtein’s ability to directly target brain magnesium levels makes it a superior choice for those seeking natural support for mental health challenges. Its focus on brain bioavailability gives it an edge over more commonly used forms like magnesium citrate or glycinate.



2, Doctor's Best, High Absorption Magnesium



Doctor's Best High Absorption Magnesium is a standout choice for managing anxiety and depression, offering a highly bioavailable chelated form of magnesium (Magnesium Glycinate/Lysinate) that is gentle on the stomach and easy to absorb. Unlike other magnesium supplements that can cause digestive discomfort, this formulation minimizes side effects while delivering therapeutic benefits for calming the nervous system and supporting neurotransmitter balance. Doctor's Best uses high-quality, non-GMO ingredients and adheres to rigorous testing standards, ensuring purity and potency. Compared to other brands, its focus on absorption and digestive tolerance makes it an excellent option for individuals seeking natural relief from stress, anxiety, and mood disorders.



3, Jamieson Magnesium Ultra Strength





Jamieson Magnesium Ultra Strength is an effective magnesium supplement that provides high-dose magnesium citrate to support anxiety and depression. With 250 mg of magnesium per serving, it offers a potent dose to help relax the nervous system, improve mood, and reduce stress. What sets Jamieson apart is its focus on bioavailability, as magnesium citrate is known for its good absorption and gentle effect on the digestive system. Jamieson also stands out for its commitment to quality, using non-GMO ingredients and ensuring rigorous testing for potency and purity. Compared to other brands, its strength and focus on bioavailability make it an excellent choice for those seeking a high-potency, effective solution for mental health support.





Dosage and Safety

Dosage is crucial when using magnesium supplements. The recommended daily intake for adults ranges from 310 to 420 mg, depending on age and gender.

Starting with a lower dose is wise to avoid potential side effects like diarrhea or stomach upset.

It is also beneficial to consult a healthcare provider, especially if other medications are being taken. Regular monitoring is recommended to ensure the supplement is effective and safe.

Maintaining awareness about magnesium levels in the body will help in adjusting dosage as needed.


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Best Fish Oil for Anxiety and Depression: A Comprehensive Guide to Top Options

 


Fish oil has gained attention for its potential benefits in mental health, particularly regarding anxiety and depression. Research suggests that omega-3 fatty acids, found in fish oil, can help reduce symptoms of these conditions. Many individuals are exploring natural supplements to support their mental well-being, and fish oil is a popular option.

When considering fish oil, not all products are created equal. Factors such as purity, concentration of omega-3s, and overall formulation can significantly impact effectiveness. Identifying the best fish oil for anxiety and depression involves evaluating these criteria to ensure optimal benefits.

Readers interested in addressing anxiety and depression through natural means will find valuable insights here. The discussion will explore top-rated fish oil products, their key ingredients, and how they may improve mental health outcomes.

Understanding Fish Oil

Fish oil is rich in omega-3 fatty acids, essential nutrients that play a significant role in various bodily functions. These components can influence mental health markedly, particularly concerning anxiety and depression.

Components of Fish Oil

Fish oil primarily contains two types of omega-3 fatty acids: EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid). Both are crucial for brain health.

  • EPA: Primarily known for its anti-inflammatory properties, EPA may help reduce symptoms of depression by modulating mood-regulating neurotransmitters.

  • DHA: This component is vital for cognitive function and is a major structural component in brain tissue. Proper levels of DHA are linked to improved mental clarity and emotional well-being.

Fish oil can be sourced from various fish, such as salmon, mackerel, and sardines. Additionally, algal oil is a plant-based source rich in DHA, appealing to vegetarians and vegans.

How Fish Oil Benefits Mental Health

Research indicates that omega-3 fatty acids in fish oil may provide notable benefits for mental health. Evidence suggests that supplementation can lead to decreased symptoms of depression and anxiety.

  • Mood Regulation: Omega-3s help balance neurotransmitter function, essential for mood stability.

  • Inflammation Reduction: By reducing neuroinflammation, fish oil may diminish depressive symptoms.

Multiple studies highlight the potential effectiveness of fish oil in adjunctive therapy for major depressive disorder. While it is not a standalone treatment, incorporating fish oil into a health regimen may offer additional support for those struggling with anxiety and depression.

Selecting the Best Fish Oil Supplement

Choosing a suitable fish oil supplement involves evaluating quality, efficacy, and product options. Careful consideration of specific criteria ensures the selection of the most beneficial oils for anxiety and depression.

Criteria for High-Quality Fish Oil

When evaluating fish oil supplements, several criteria are essential.

  1. EPA and DHA Content: The effectiveness of fish oil largely stems from its omega-3 fatty acids, specifically EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid). A high ratio of these components is vital for mental health benefits.

  2. Purity and Freshness: Look for oils that are tested for heavy metals, PCBs, and other contaminants. Third-party testing can validate these claims and ensure products are free from harmful substances.

  3. Source of Fish: Supplements derived from wild-caught fish are typically more potent and sustainable than those from farmed sources. Anchovies, sardines, and mackerel are preferred.

  4. Form and Absorption: Fish oil comes in several forms, including triglycerides, ethyl esters, and phospholipids. Triglyceride forms are generally more easily absorbed.

Top Fish Oil Products for Anxiety and Depression

Several highly rated fish oil supplements cater specifically to mental health needs.

Nordic Naturals Ultimate Omega


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California Gold Nutrition, Omega 800 Ultra-Concentrated



https://ca.iherb.com/pr/california-gold-nutrition-omega-3-premium-fish-oil-100-fish-gelatin-softgels/62118

Kirkland Signature Super Concentrate Omega 3


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1NordicNaturals Ultimate Omega:

Nordic Naturals Ultimate Omega stands out as one of the best fish oil supplements for anxiety and depression due to its exceptional purity, potency, and bioavailability. Unlike many other brands, Nordic Naturals uses sustainably sourced, wild-caught fish and ensures its oils are purified through a state-of-the-art molecular distillation process to remove heavy metals, PCBs, and other toxins. The high concentration of EPA and DHA in each serving surpasses the levels found in many competing products, providing therapeutic doses necessary for supporting brain health and mood regulation. Additionally, their triglyceride form of omega-3s is easier for the body to absorb compared to the ethyl ester form used by many other brands, ensuring maximum effectiveness. Backed by third-party testing and certification for quality, Nordic Naturals is a trusted choice for those seeking targeted support for anxiety and depression.



2California Gold Nutrition Omega 800 Ultra-Concentrated

California Gold Nutrition Omega 800 Ultra-Concentrated stands out from other omega-3 supplements due to its exceptional potency, quality, and value. Each soft gel delivers 800 mg of EPA and DHA in the superior triglyceride form, which is more bioavailable and better absorbed than the ethyl ester form used by many other brands. The fish oil is sustainably sourced and undergoes stringent molecular distillation to remove heavy metals, PCBs, and other contaminants, ensuring purity and safety. Additionally, California Gold Nutrition is manufactured in cGMP-compliant facilities and undergoes rigorous third-party testing for potency and quality, providing reassurance for consumers. Compared to competitors, this brand offers higher doses of essential omega-3s in fewer capsules, making it a cost-effective and convenient choice for individuals seeking to reduce anxiety and depression naturally.



3Kirkland Signature Super Concentrate Omega 3

Kirkland Signature Super Concentrate Omega-3 stands out as a high-value option for anxiety and depression due to its robust formulation and affordability. Each soft gel contains 410 mg of EPA and 274 mg of DHA, providing the therapeutic levels of omega-3s needed to support brain health, reduce inflammation, and regulate mood. Unlike many budget-friendly brands, Kirkland ensures purity through a molecular distillation process to remove mercury, PCBs, and other toxins, meeting stringent quality standards. While it uses the ethyl ester form rather than the triglyceride form found in premium brands, it still delivers effective results for most users. For individuals seeking a cost-effective yet potent supplement, Kirkland Signature offers a dependable choice with a strong focus on safety and efficacy.



Usage and Dosage Recommendations

Appropriate dosage of fish oil varies based on individual needs and health conditions. Generally, clinical studies suggest a dosage of 1,000–2,000 mg of combined EPA and DHA per day for those addressing anxiety and depression.

  1. Consult a Healthcare Provider: Before starting any supplement, it is advised to consult a healthcare professional, especially for individuals on medications or with pre-existing conditions.

  2. Consistency Is Key: Regular intake is crucial for seeing benefits. Users may need to allow several weeks for noticeable changes in mood stability.

  3. Monitor for Side Effects: While fish oil is generally safe, some individuals may experience mild gastrointestinal issues. Reducing the dose or taking it with meals may alleviate these symptoms.


Sunday, January 5, 2025

Magnesium can help with Anxiety and Depression

 


What is magnesium?


Magnesium is a nutrient that is important for many basic functions and processes in the body. It helps ensure your nerves are working properly and keep your blood sugar and blood pressure at the correct level.


Magnesium comes from the foods and supplements we eat. If you don't have enough magnesium in your body, you may experience symptoms such as headaches, loss of appetite, nausea, vomiting, fatigue and weakness.


Can Magnesium help with Anxiety and Depression?


Magnesium is good for your health, but it's not totally clear how it affects anxiety. Scientists are still trying to figure that out, but some studies have shown that magnesium can help reduce some stress and anxiety symptoms. Here's what we know so far:


In a 2006 case study [1], several patients with Major Depressive Disorder (MDD) took 125 mg-300 mg of higher bioavailability forms of Magnesium (Magnesium glycinate) and Magnesium taurine after every meal and just before going to sleep. The patients’ symptoms improved significantly in just a few hours. The researcher noted that people who are deficient in Magnesium may be especially sensitive to high levels of Calcium. Magnesium and Calcium compete for absorption. Too high of one causes the other to be too low.


In modern diets, Magnesium is usually the least available. Thus, foods with high Calcium content (such as milk) (10:1 Calcium to Magnesium) should be avoided at least temporarily for people with Magnesium deficiency.


A double-blind control group clinical trial in 2008 [2]. 23 elderly people who suffered from diabetes, depression and magnesium deficiency (serum magnesium <1.8mg/dL) were divided into two groups for the test, one group took magnesium chloride Magnesium (MgCl2), another tricyclic antidepressant (imipramine), showed that after 12 weeks, both magnesium and the antidepressant were equally effective in treating depressive symptoms in patients taking the magnesium group, Serum magnesium levels also increased substantially. The conclusion of the study was that magnesium supplementation was as effective for depression as tricyclic antidepressants in magnesium-deficient depressed patients.


In a double-blind control group clinical study in 2015 [3], 60 depressed patients with magnesium deficiency were divided into two groups, one group supplemented with 500 mg of magnesium (MgO) per day, and the other group took a placebo. After 8 weeks, 88.5% of the subjects in the intervention group returned to the normal range of serum magnesium, and the improvement in depression was significantly greater than that in the control group. The conclusion of the study is that taking 500mg of MgO over 8 weeks can improve the condition of depressed patients with magnesium deficiency.


What about depressed patients who are not magnesium deficient? In another randomized controlled clinical trial in 2017 [4], 126 patients with depression were divided into two groups, one group took 500 mg of magnesium (MgO) per day, and the other took a placebo. After six weeks, symptoms of depression and anxiety improved significantly in the magnesium group. Moreover, 83% of the subjects who took magnesium completed the test, and 61% of the subjects indicated that they would continue to use magnesium in the future, which proves that the side effects of magnesium are not great. The conclusion of the study is that taking 500mg of magnesium (MgO, which contains 248mg of magnesium element) per day can significantly reduce the symptoms of depression and anxiety.


However, there are also clinical studies showing that magnesium has no effect on depression. In 2018, a Polish scholar conducted another clinical trial on 37 subjects [5], taking 120 mg of magnesium (magnesium aspartate, Mg Aspartate) every day. ), the results proved that magnesium supplementation can be helpful for depression, but the researchers put forward an interpretation that the dose and form used affected the results of the study, and the effect of using high doses and high bioavailability of magnesium on the treatment of depression would be better a lot of. However, the scholars of the study believed that the magnesium aspartate (Magnesium Aspartate) and magnesium chloride (MgCl2) they used were already bioavailable forms of magnesium, which was not the case, but discussing the bioavailability of various magnesium forms has exceeded The scope of this article can only be introduced in another article in the future.


In a double-blind control group clinical study in 2007 [6], 94 female college students were divided into two groups to conduct a treatment trial for premenstrual syndrome. The test group took 80 mg of B6 pyridoxine (pyridoxine) every day for 2 consecutive months. Compared with the control group, there was no effect. If the above-mentioned 1998 and 2000 clinical trials using MgO were due to the technical limitations of those years, this 2007 clinical trial reflects the lack of understanding of the activity of vitamin B6 by the responsible researchers, and the effect of pyridoxine form of B6 on improving The effect of B6 concentration in the blood is very different from that of P5P.


Benefits of magnesium for mental health


  • one of the reasons why magnesium might help reduce anxiety is that it may improve brain function. Research shows that magnesium plays an important role in regulating neurotransmitters, which send messages throughout the brain and body. This is how magnesium plays a role in neurological health. [7]


  • Magnesium has been found to have a positive effect on brain health and can help lower stress and anxiety levels. It's thought to work in the hypothalamus in the brain, which is responsible for regulating the adrenal and pituitary glands, which are responsible for how your body reacts to stress. If your body doesn't have enough magnesium, it can make stress worse, and if your body is under a lot of stress, it can make your magnesium levels lower. [8]


  • One of the body's responses to stress and anxiety is muscle tension. Magnesium is an essential nutrient for muscle function and helps muscle tissue relax. Magnesium deficiency can increase muscle tension and cramps. [9]


  • Magnesium may help improve sleep quality by regulating the neurotransmitter GABA, which is important for sleep. Magnesium's role in lowering muscle tension and regulating the nervous system may also help improve nighttime sleep. [10]


  • One of the reasons magnesium may help reduce anxiety is because it may help improve brain function. Studies have shown that magnesium is involved in the regulation of neurotransmitters. These neurotransmitters are responsible for sending messages to and from the brain and the rest of the body. In other words, magnesium is involved in neurological health. [11]


What form of magnesium is best for anxiety or depression?


There are two main factors to consider when choosing a form of magnesium:


1. Bioavailability, which indicates how much magnesium the gut can absorb.

2. Enter the brain, since the effective form of magnesium must be able to cross the protective blood-brain barrier that surrounds the brain.


The two most commonly used forms of magnesium—magnesia and citrate—have the lowest bioavailability of the various forms. This means they are more likely to pass through the gut and cause loose stools and diarrhea, so they are best used to relieve constipation. Magnesium salts such as carbonates and sulfates have similar absorption problems.


According to recent research, certain forms of magnesium have better bioavailability and better ability to cross the blood brain, making them a better treatment option for addressing symptoms of anxiety and depression:


Magnesium Taurate


Magnesium taurate contains an amino acid called taurine, which has calming, neuroprotective and anti-inflammatory effects on the brain. Taurine also seems to help magnesium get into the brain. In addition, it is gentle on the gastrointestinal tract and less likely to cause loose stools and diarrhea. In a recent study, magnesium acetyltaurate increased magnesium levels in the brain more than any other form of magnesium.


Magnesium Threonate


This form of magnesium has impressive research supporting its use in mental health conditions and evidence that it can cross the blood-brain barrier. However, it can be more expensive and may require 2-3 times more capsules than other magnesium supplements to achieve an adequate therapeutic dose.



Magnesium Glycinate


Glycine is an essential amino acid with important neurotransmitter functions in the brain. Supplementing with glycine may improve sleep quality, making this form of magnesium a good choice for people with insomnia. Preliminary research suggests that magnesium glycinate may increase magnesium levels in brain tissue. Like magnesium taurate, the glycinate form is gentle on the GI tract.


Magnesium Malate


This is one of the better absorbed forms of magnesium, increasing serum and muscle magnesium levels. Preliminary research suggests that it may be effective in treating fibromyalgia and chronic fatigue symptoms, since malic acid is associated with energy production.


Based on current data, magnesium taurate and magnesium glycinate have the most research supporting their effects on anxiety and other mental health disorders. Magnesium malate and threonine have also been shown to be therapeutic and may be useful in many cases of psychosis. [12][13]


What are the side effects of magnesium supplementation? is it safe?


Magnesium is generally very safe, and serious side effects and toxicity are rare.


For most people, the body effectively disposes of excess magnesium by excreting it through the stool, which is why the most common side effect is loose stools or diarrhea.


Although magnesium rarely reaches toxic levels, symptoms of toxicity include a drop in blood pressure, drowsiness, confusion, irregular heartbeat, dizziness, muscle weakness, and difficulty breathing. Patients with impaired renal function are at higher risk of adverse effects of magnesium. Magnesium can also interfere with certain medications, including various antibiotics and medications for diabetes or high blood pressure. If any of the above conditions occur, be sure to consult your physician before starting magnesium supplementation. [14]


Ref:

[1] Eby, George & Eby, Karen. (2006). Rapid recovery from major depression using magnesium treatment. Medical hypotheses. 67. 362-70. 10.1016/j.mehy.2006.01.047. https://doi.org/10.1016/j.mehy.2006.01.047

[2]Barragán-Rodríguez, Lazaro & Rodríguez-Morán, Martha & Guerrero-Romero, Fernando. (2008). Efficacy and safety of oral magnesium supplementation in the treatment of depression in the elderly with type 2 diabetes: A randomized, equivalent trial. Magnesium research : official organ of the International Society for the Development of Research on Magnesium. 21. 218-23. 10.1684/mrh.2008.0149. https://pubmed.ncbi.nlm.nih.gov/19271419/

[3] Rajizadeh, Afsaneh & Mozaffari-khosravi, Hassan & Yassini, Mojtaba & Dehghani, Ali. (2016). The Effect of Magnesium Supplementation on Depression Status in Depressed Patients with Magnesium Deficiency: A Randomized, Double-blind, Placebo-Controlled Trial. Nutrition. 35. 10.1016/j.nut.2016.10.014. https://doi.org/10.1016/j.nut.2016.10.014

[4] Tarleton, Emily & Littenberg, Benjamin & Maclean, Charles & Kennedy, Amanda & Daley, Christopher. (2017). Role of magnesium supplementation in the treatment of depression: A randomized clinical trial. PLOS ONE. 12. e0180067. 10.1371/journal.pone.0180067. https://doi.org/10.1371/journal.pone.0180067

[5] Pilc, Andrzej. (2018). Effects of Magnesium Supplementation on Unipolar Depression: A Placebo-Controlled Study and Review of the Importance of Dosing and Magnesium Status in the Therapeutic Response. Nutrients. 10. 1014. 10.3390/nu10081014.

[6] Kashanian M, Mazinani R, Jalalmanesh S. (2007), Pyridoxine (vitamin B6) therapy for premenstrual syndrome. Int J Gynecol Obstet 2007;96(1):43–4. https://doi.org/10.1016/j.ijgo.2006.09.014

[7]Kirkland AE, Sarlo GL, Holton KF. The Role of Magnesium in Neurological Disorders. Nutrients. 2018 Jun 6;10(6):730. doi: 10.3390/nu10060730. PMID: 29882776; PMCID: PMC6024559.

[8]S.B. Sartori, N. Whittle, A. Hetzenauer, N. Singewald, Magnesium deficiency induces anxiety and HPA axis dysregulation: Modulation by therapeutic drug treatment,Neuropharmacology,Volume 62, Issue 1,2012,https://doi.org/10.1016/j.neuropharm.2011.07.027.

[9]Zhang Y, Xun P, Wang R, Mao L, He K. Can Magnesium Enhance Exercise Performance? Nutrients. 2017 Aug 28;9(9):946. doi: 10.3390/nu9090946. PMID: 28846654; PMCID: PMC5622706.

[10]Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, Rashidkhani B. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012 Dec;17(12):1161-9. PMID: 23853635; PMCID: PMC3703169.

[11]Kirkland AE, Sarlo GL, Holton KF. The Role of Magnesium in Neurological Disorders. Nutrients. 2018 Jun 6;10(6):730. doi: 10.3390/nu10060730. PMID: 29882776; PMCID: PMC6024559.

[12]Uysal, N., Kizildag, S., Yuce, Z. et al. Timeline (Bioavailability) of Magnesium Compounds in Hours: Which Magnesium Compound Works Best?. Biol Trace Elem Res 187, 128–136 (2019). https://doi.org/10.1007/s12011-018-1351-9

[13]Boyle NB, Lawton C, Dye L. The Effects of Magnesium Supplementation on Subjective Anxiety and Stress-A Systematic Review. Nutrients. 2017 Apr 26;9(5):429. doi: 10.3390/nu9050429. PMID: 28445426; PMCID: PMC5452159.

[14]Magnesium Fact Sheet for Health Professionals https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/



The Mental Health Benefits of Vitamin B Complex

 


B vitamins


• Riboflavin (B2): Riboflavin boosts antioxidant activity and energy synthesis.
• Niacin (B3): Niacin promotes healthy brain function and aids in energy production.
• Pantothenic acid (B5): Pantothenic acid supports healthy adrenal function and aids in the body's conversion of food into energy.
• Pyridoxine (B6): Vitamin B6 aids in the growth and operation of the brain as well as the synthesis of neurotransmitters that control mood.
• Biotin (B7): Biotin helps produce energy and maintains healthy skin, hair, and nails.
• Folate (B9): Folate supports the growth and maintenance of healthy cells, particularly those in the brain.
• Cobalamin (B12): B12 is necessary for the synthesis of dopamine and serotonin, two neurotransmitters that are crucial for controlling mood and emotions, as well as red blood cell development.
• A groundbreaking study, published in the Journal of Human Psychopharmacology: Clinical and Experimental, reveals that B-complex supplements are effective at reducing stress.[2] After taking B complex supplements for a period of 90 days, the participants reported experiencing significantly lower job-related stress. Additionally, they noted improvements in mood and a reduction in confusion.
In a scientific experiment conducted in 2011 using a 3-blind control group, 60 healthy patients were divided into three groups. One group received vitamin B complex vitamins, another received slow-release vitamin B, and the last group was given a placebo. After a 90-day period, there was no statistically significant difference between the two groups receiving B vitamins and the control group receiving a placebo. However, when compared to the control group, the B vitamin groups showed a significant reduction in stress levels and a simultaneous decrease in anxiety (confusion) and depressive symptoms.


Particularly the B vitamins support a healthy brain and have an immediate impact on your mood. The creation of energy, DNA/RNA synthesis and repair, the manufacture of neurochemicals and signalling molecules, as well as other components of the brain, are all impacted by B vitamins. For psychological and neurological functioning, it is important to maintain optimum amounts of vitamin B.[1]

The 8 Essential B Vitamins You Need To Know

What is the B complex exactly? For those who are unaware, B complex is made up of the eight water-soluble B vitamins listed below:

      • Thiamin (B1): Thiamin supports proper neuron function and aids in the conversion of food into energy.

     • Riboflavin (B2): Riboflavin boosts antioxidant activity and energy synthesis.

     • Niacin (B3): Niacin promotes healthy brain function and aids in energy production.

     • Pantothenic acid (B5): Pantothenic acid supports healthy adrenal function and aids in the body's conversion of food into energy.

     • Pyridoxine (B6): Vitamin B6 aids in the growth and operation of the brain as well as the synthesis of neurotransmitters that control mood.

     • Biotin (B7): Biotin helps produce energy and maintains healthy skin, hair, and nails.

     • Folate (B9): Folate supports the growth and maintenance of healthy cells, particularly those in the brain.

     • Cobalamin (B12): B12 is necessary for the synthesis of dopamine and serotonin, two neurotransmitters that are crucial for controlling mood and emotions, as well as red blood cell development.




Vitamin B foods


B vitamins are a group of water-soluble vitamins that play crucial roles in various bodily processes. They are present in numerous natural, unprocessed foods and can also be obtained in the form of dietary supplements.


The following foods are rich in B vitamins:[1]


B1 Cereals (esp. whole grain), brown rice, green vegetables, potatoes, pasta, liver, pork, eggs

B2 Dairy products, leafy vegetables, legumes, liver, kidneys, yeast, mushrooms

B3 Meat, fish, whole grain cereal, legumes, mushrooms, nuts

B5 Meat, whole grain cereals, broccoli

B6 Meat, fish, legumes, nuts, bananas, potatoes

B7 Eggs, liver, pork, leafy vegetables

B9 Leafy vegetables, legumes, citrus fruits

B12 Meat, fish and other animal products



Vitamin B Complex benefits for mental health


Let's get to the main question you're interested in: can B vitamins help with anxiety and depression? Science says that the answer is indeed. Here are a few research that show how B-complex vitamins might reduce anxiety and depression symptoms:



In 2015, a double-blind, controlled clinical trial investigated the effectiveness of multivitamins [4]. The study involved 58 healthy participants in both a control group and an intervention group. After 4 weeks, the intervention group received multivitamins enriched with various B vitamins. The levels of vitamin B in their blood significantly increased, and the inflammatory marker homocysteine noticeably decreased. Subsequent research also found that the intervention group reported improved mood and fewer symptoms of depression.

In a 2000 clinical trial featuring a double-blind control group [5], a total of 80 healthy participants were split into an intervention group and a control group. The intervention group received a daily regimen of vitamin B-based multivitamins. After 28 days, the intervention group experienced a notable reduction in anxiety symptoms.

A 2004 research [6] examined 140 people, 18 of whom (13%) reported depressive symptoms. The study revealed that P5P blood levels are linked to depression by showing that the lower the active B6 (P5P) concentration in the blood, the more sad symptoms are present.

In a 2015 Canadian study involving 170 participants over a span of 3 years [7], it was found that individuals with the highest levels of B6 had a 43% lower risk of experiencing depression. Although this study was observational in nature, it took into account additional factors and the overall health status of the subjects in the risk analysis.

A recent meta-analysis involving over 7,000 individuals examined the connection between B vitamins and mental health [8]. The research indicated that higher vitamin B intake was associated with a lower prevalence of stress, sadness, and anxiety. Moreover, lower levels of vitamin B6 were linked to a greater likelihood of experiencing stress. Adequate intake of vitamins B1, B3, and B5 was also associated with reduced anxiety. Furthermore, meeting the recommended intake of folic acid was linked to a reduction in depression.

A 2017 systematic study revealed how different micronutrients affect women's stress levels. Older women who take pyridoxine alone experience less anxiety. Magnesium and vitamin B6 may also lessen premenstrual anxiety, in addition to vitamin C for lowering stress-induced anxiety. Another comparable study verified[9] that magnesium and vitamin B6 were superior to magnesium alone in lowering stress.

You can see that B-complex Stress Relief Complex is more than simply a catchy name for a product. Scientific evidence is available to back up this health claim from a large number of research and clinical trials.



The role of vitamin b complex in relieving anxiety and depression

1, There is a negative correlation between your body's homocysteine levels and B vitamins.


Homocysteine is an amino acid that can accumulate in significant quantities when you consume a diet high in meat. Research has shown that individuals suffering from depression and having a deficiency in B vitamins tend to have higher homocysteine levels. [10-a] [11]This connection between B vitamins and homocysteine arises from the fact that vitamins B6, B9, and B12 play a crucial role in converting homocysteine into the essential amino acids methionine, cysteine, and S-adenosine methionine (SAM), which are vital for neurological functions. When these conversions don't occur as they should, it can lead to depressive symptoms.[12][13] Therefore, ensuring your body receives an adequate supply of these essential B vitamins can help regulate homocysteine levels, ultimately leading to an improvement in your mood.


Another possible mechanism for the link between homocysteine and anxiety is that dysregulation of homocysteine-related methylation is associated with oxidative stress in the brain. A recent animal study [14]showed that excessive consumption of methionine led to elevated homocysteine levels, leading to increased anxiety-related behaviors in rats. The anxiety-inducing effects in these mice may be due to oxidative stress in the brain.


2, Vitamin B participates in the synthesis of nerve cells and promotes nerve cells growth


B vitamins can provide cell energy, synthesize myelin and neurotransmitters in nerve cells, and have the functions of antioxidant protection and nerve protection. [1][15] The neurotropic B vitamins thiamine (B1), pyridoxine (B6), and cobalamin (B12) are key players, maintaining neuronal vitality in different ways. Vitamin B1 serves as a cofactor for glucose metabolism, providing energy to indirectly support the synthesis of nucleic acids, neurotransmitters, myelin, etc. Additionally, it is thought to aid in antioxidant mechanisms. [16][17] Vitamin B6 is mainly involved in neuroprotection, [21][22] The main function of vitamin B12 is to promote the synthesis of myelin, thereby promoting the regeneration of peripheral nerves. [18][19][20]


3, Vitamin B complex helps restore dopamine and serotonin levels.


Stress impairs the body's capacity to create dopamine, the brain neurotransmitter associated with pleasure. Serotonin, frequently referred to as the "happy chemical" that controls mood, is also impacted by stress. Together, these molecular alterations help to explain why feeling stressed makes you more likely to experience unpleasant emotions like sorrow and rage.


Vitamins B2 and B6 have been shown in a 2018 rat model research[23] to help restore dopamine levels and lower oxidative stress. Most significantly, pyridoxine aids[24][25] in the synthesis of red blood cells, dopamine, serotonin, and gamma-aminobutyric acid (also known as GABA, a relaxing brain chemical).


Last but not least, another B vitamin promoted for its ability to reduce stress is folic acid. Serotonin, adrenaline, and dopamine are all produced by vitamin B9.[26] This antioxidant is frequently deficient in depressive disorders.[27]


4,Vitamin B complex helps improve adrenal gland function


The adrenal glands, which control stress-related chemicals including cortisol and adrenaline, can suffer damage from both emotional and physical stress. Fortunately, research suggests that taking additional B vitamins, particularly B1, B6, and B12, may improve adrenal function and increase the stress response.[28]


B-Complex Stress Support Works Better Overall


It has been widely accepted in the scientific literature that certain B vitamins have a positive effect on mental health. However, it has been suggested that selecting specific vitamins may not be the most effective approach.


Instead, it is recommended to incorporate all eight B vitamins[10] into one's diet. This is due to the fact that they all work together to reduce stress levels through various biological processes. Additionally, a meta-analysis conducted in 2013 further supported this conclusion. Furthermore, research has shown that supplementing multivitamins with higher doses of B vitamins is more effective in reducing stress and improving mental health in healthy individuals.




REF

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